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Single-molecule imaging reveals a collapsed conformational state for DNA-bound cohesin

Cohesin is essential for the hierarchical organization of the eukaryotic genome and plays key roles in many aspects of chromosome biology. The conformation of cohesin bound to DNA remains poorly defined, leaving crucial gaps in our understanding of how cohesin fulfills its biological functions. Here...

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Foilsithe in:Cell Rep
Main Authors: Stigler, Johannes, Çamdere, Gamze Ö., Koshland, Douglas E., Greene, Eric C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856582/
https://ncbi.nlm.nih.gov/pubmed/27117417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.003
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