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Intermediate step of cohesin’s ATPase cycle allows cohesin to entrap DNA

Cohesin is a four-subunit ATPase in the family of structural maintenance of chromosomes (SMC). Cohesin promotes sister chromatid cohesion, chromosome condensation, DNA repair, and transcription regulation. Cohesin performs these functions as a DNA tether and potentially a DNA-based motor. At least o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Çamdere, Gamze Ö., Carlborg, Kristian K., Koshland, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166799/
https://ncbi.nlm.nih.gov/pubmed/30201721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807213115
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