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The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering

Cohesin tethers together regions of DNA, thereby mediating higher order chromatin organization that is critical for sister chromatid cohesion, DNA repair and transcriptional regulation. Cohesin contains a heterodimeric ATP-binding Cassette (ABC) ATPase comprised of Smc1 and Smc3 ATPase active sites....

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Çamdere, Gamze, Guacci, Vincent, Stricklin, Jeremiah, Koshland, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709263/
https://ncbi.nlm.nih.gov/pubmed/26583750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11315
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