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Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis

Both the WNT/β-catenin and hedgehog signaling pathways are important in the regulation of limb development, chondrocyte differentiation, and degeneration of articular cartilage in osteoarthritis (OA). It is not clear how these signaling pathways interact in interzone cell differentiation and synovia...

詳細記述

保存先:
書誌詳細
出版年:J Clin Invest
主要な著者: Rockel, Jason S., Yu, Chunying, Whetstone, Heather, Craft, April M., Reilly, Katherine, Ma, Henry, Tsushima, Hidetoshi, Puviindran, Vijitha, Al-Jazrawe, Mushriq, Keller, Gordon M., Alman, Benjamin A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855923/
https://ncbi.nlm.nih.gov/pubmed/27018594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80205
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