Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3

Middle East respiratory syndrome coronavirus (MERS-CoV) infection has claimed hundreds of lives and has become a global threat since its emergence in Saudi Arabia in 2012. The ability of MERS-CoV to evade the host innate antiviral response may contribute to its severe pathogenesis. Many MERS-CoV-enc...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Lui, Pak-Yin, Wong, Lok-Yin Roy, Fung, Cheuk-Lai, Siu, Kam-Leung, Yeung, Man-Lung, Yuen, Kit-San, Chan, Chi-Ping, Woo, Patrick Chiu-Yat, Yuen, Kwok-Yung, Jin, Dong-Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855074/
https://ncbi.nlm.nih.gov/pubmed/27094905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2016.33
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