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Middle East Respiratory Syndrome Coronavirus 4a Protein Is a Double-Stranded RNA-Binding Protein That Suppresses PACT-Induced Activation of RIG-I and MDA5 in the Innate Antiviral Response

Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging pathogen that causes severe disease in human. MERS-CoV is closely related to bat coronaviruses HKU4 and HKU5. Evasion of the innate antiviral response might contribute significantly to MERS-CoV pathogenesis, but the mechanism is...

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Библиографические подробности
Главные авторы: Siu, Kam-Leung, Yeung, Man Lung, Kok, Kin-Hang, Yuen, Kit-San, Kew, Chun, Lui, Pak-Yin, Chan, Chi-Ping, Tse, Herman, Woo, Patrick C. Y., Yuen, Kwok-Yung, Jin, Dong-Yan
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993821/
https://ncbi.nlm.nih.gov/pubmed/24522921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03649-13
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