Suppression of PACT-Induced Type I Interferon Production by Herpes Simplex Virus 1 Us11 Protein

Herpes simplex virus 1 (HSV-1) Us11 protein is a double-stranded RNA-binding protein that suppresses type I interferon production through the inhibition of the cytoplasmic RNA sensor RIG-I. Whether additional cellular mediators are involved in this suppression remains to be determined. In this study...

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Detalhes bibliográficos
Main Authors: Kew, Chun, Lui, Pak-Yin, Chan, Chi-Ping, Liu, Xiang, Au, Shannon Wing Ngor, Mohr, Ian, Jin, Dong-Yan, Kok, Kin-Hang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838286/
https://ncbi.nlm.nih.gov/pubmed/24067967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02564-13
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