NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

NLRs (nucleotide-binding domain [NBD] leucine-rich repeat [LRR]–containing proteins) exhibit diverse functions in innate and adaptive immunity. NAIPs (NLR family, apoptosis inhibitory proteins) are NLRs that appear to function as cytosolic immunoreceptors for specific bacterial proteins, including f...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Rauch, Isabella, Tenthorey, Jeannette L., Nichols, Randilea D., Al Moussawi, Khatoun, Kang, James J., Kang, Chulho, Kazmierczak, Barbara I., Vance, Russell E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854734/
https://ncbi.nlm.nih.gov/pubmed/27045008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151809
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