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Cryo-EM studies of NAIP–NLRC4 inflammasomes

The NAIP–NLRC4 family of inflammasomes are components of the innate immune system that sound a molecular alarm in the presence of intracellular pathogens. In this chapter, we provide an in-depth guide to using cryo-electron microscopy (cryo-EM) to investigate these inflammasomes, focusing especially...

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Publicado en:Methods Enzymol
Main Authors: Haloupek, Nicole, Grob, Patricia, Tenthorey, Jeannette, Vance, Russell E., Nogales, Eva
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7025759/
https://ncbi.nlm.nih.gov/pubmed/31455527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.04.030
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