Differential Requirements for NAIP5 in Activation of the NLRC4 Inflammasome

Inflammasomes are cytosolic multiprotein complexes that assemble in response to infectious or noxious stimuli and activate the CASPASE-1 protease. The inflammasome containing the nucleotide binding domain-leucine-rich repeat (NBD-LRR) protein NLRC4 (interleukin-converting enzyme protease-activating...

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Autori principali: Lightfield, Karla L., Persson, Jenny, Trinidad, Norver J., Brubaker, Sky W., Kofoed, Eric M., Sauer, John-Demian, Dunipace, Eric A., Warren, Sarah E., Miao, Edward A., Vance, Russell E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067536/
https://ncbi.nlm.nih.gov/pubmed/21282416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01187-10
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