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Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes
NLR (nucleotide-binding domain [NBD]- and leucine-rich repeat [LRR]-containing) proteins mediate innate immune sensing of pathogens in mammals and plants. How NLRs detect their cognate stimuli remains poorly understood. Here, we analyzed ligand recognition by NAIP (NLR Apoptosis Inhibitory Protein)...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988258/ https://ncbi.nlm.nih.gov/pubmed/24657167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.018 |
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