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Molecular basis for specific recognition of bacterial ligands by NAIP/NLRC4 inflammasomes

NLR (nucleotide-binding domain [NBD]- and leucine-rich repeat [LRR]-containing) proteins mediate innate immune sensing of pathogens in mammals and plants. How NLRs detect their cognate stimuli remains poorly understood. Here, we analyzed ligand recognition by NAIP (NLR Apoptosis Inhibitory Protein)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tenthorey, Jeannette L., Kofoed, Eric M., Daugherty, Matthew D., Malik, Harmit S., Vance, Russell E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988258/
https://ncbi.nlm.nih.gov/pubmed/24657167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.018
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