NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

NLRs (nucleotide-binding domain [NBD] leucine-rich repeat [LRR]–containing proteins) exhibit diverse functions in innate and adaptive immunity. NAIPs (NLR family, apoptosis inhibitory proteins) are NLRs that appear to function as cytosolic immunoreceptors for specific bacterial proteins, including f...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Rauch, Isabella, Tenthorey, Jeannette L., Nichols, Randilea D., Al Moussawi, Khatoun, Kang, James J., Kang, Chulho, Kazmierczak, Barbara I., Vance, Russell E.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854734/
https://ncbi.nlm.nih.gov/pubmed/27045008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151809
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