NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

NLRs (nucleotide-binding domain [NBD] leucine-rich repeat [LRR]–containing proteins) exhibit diverse functions in innate and adaptive immunity. NAIPs (NLR family, apoptosis inhibitory proteins) are NLRs that appear to function as cytosolic immunoreceptors for specific bacterial proteins, including f...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Rauch, Isabella, Tenthorey, Jeannette L., Nichols, Randilea D., Al Moussawi, Khatoun, Kang, James J., Kang, Chulho, Kazmierczak, Barbara I., Vance, Russell E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2016
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854734/
https://ncbi.nlm.nih.gov/pubmed/27045008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151809
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