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Tandem Rh-Catalysis: Decarboxylative β-Keto Acid and Alkyne Cross-Coupling

Herein, we describe a regioselective Rh-catalyzed decarboxylative cross-coupling of β–keto acids and alkynes to access branched γ,δ–unsaturated ketones. Rh-hydride catalysis enables the isomerization of an alkyne to generate a metal-allyl species that can undergo carbon-carbon bond formation. Ketone...

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Bibliografiske detaljer
Udgivet i:Chem Commun (Camb)
Main Authors: Cruz, Faben A., Chen, Zhiwei, Kurtoic, Sarah I., Dong, Vy M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851867/
https://ncbi.nlm.nih.gov/pubmed/27043656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc02522f
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