A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer’s disease

BACKGROUND: Clinical failures singularly targeting amyloid-β pathology indicate a critical need for alternative Alzheimer’s disease (AD) therapeutic strategies. The mixed pathology reported in a large population of AD patients demands a multifunctional drug approach. Since activation of cAMP respons...

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Publicado en:Mol Neurodegener
Autores principales: Luo, Jia, Lee, Sue H., VandeVrede, Lawren, Qin, Zhihui, Ben Aissa, Manel, Larson, John, Teich, Andrew F., Arancio, Ottavio, D’Souza, Yohan, Elharram, Ahmed, Koster, Kevin, Tai, Leon M., LaDu, Mary Jo, Bennett, Brian M., Thatcher, Gregory R. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850651/
https://ncbi.nlm.nih.gov/pubmed/27129593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0103-6
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