A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer’s disease

BACKGROUND: Clinical failures singularly targeting amyloid-β pathology indicate a critical need for alternative Alzheimer’s disease (AD) therapeutic strategies. The mixed pathology reported in a large population of AD patients demands a multifunctional drug approach. Since activation of cAMP respons...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Neurodegener
Prif Awduron: Luo, Jia, Lee, Sue H., VandeVrede, Lawren, Qin, Zhihui, Ben Aissa, Manel, Larson, John, Teich, Andrew F., Arancio, Ottavio, D’Souza, Yohan, Elharram, Ahmed, Koster, Kevin, Tai, Leon M., LaDu, Mary Jo, Bennett, Brian M., Thatcher, Gregory R. J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850651/
https://ncbi.nlm.nih.gov/pubmed/27129593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0103-6
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