A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer’s disease

BACKGROUND: Clinical failures singularly targeting amyloid-β pathology indicate a critical need for alternative Alzheimer’s disease (AD) therapeutic strategies. The mixed pathology reported in a large population of AD patients demands a multifunctional drug approach. Since activation of cAMP respons...

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Detaylı Bibliyografya
Yayımlandı:Mol Neurodegener
Asıl Yazarlar: Luo, Jia, Lee, Sue H., VandeVrede, Lawren, Qin, Zhihui, Ben Aissa, Manel, Larson, John, Teich, Andrew F., Arancio, Ottavio, D’Souza, Yohan, Elharram, Ahmed, Koster, Kevin, Tai, Leon M., LaDu, Mary Jo, Bennett, Brian M., Thatcher, Gregory R. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850651/
https://ncbi.nlm.nih.gov/pubmed/27129593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0103-6
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