NO/cGMP/pCREB re-activation reverses cognition deficits and attenuates amyloid-β neuropathology in transgenic models of Alzheimer’s disease

Eitemau Tebyg

• Discovery of neuroprotective soluble guanylate cyclase modulators (GCMs) aciting via NO/GC/cGMP/CREB pathway
  gan: Siklos, Marton I, et al.
  Cyhoeddwyd: (2013)
• Pharmacological manipulation of cGMP and NO/cGMP in CNS drug discovery
  gan: Hollas, Michael A., et al.
  Cyhoeddwyd: (2018)
• An NO Donor Approach to Neuroprotective and Procognitive Estrogen Therapy Overcomes Loss of NO Synthase Function and Potentially Thrombotic Risk
  gan: VandeVrede, Lawren, et al.
  Cyhoeddwyd: (2013)
• Transgenic Mice for cGMP Imaging
  gan: Thunemann, Martin, et al.
  Cyhoeddwyd: (2013)
• Analysis of cGMP signalling with transgenic mice expressing FRET-based cGMP sensors
  gan: Wen, Lai, et al.
  Cyhoeddwyd: (2013)