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Rapidly Translated Polypeptides Are Preferred Substrates for Cotranslational Protein Degradation

Nascent polypeptides are degraded by the proteasome concurrently with their synthesis on the ribosome. This process, called cotranslational protein degradation (CTPD), has been observed for years, but the underlying mechanisms remain poorly understood. Equally unclear are the identities of cellular...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Ha, Seung-Wook, Ju, Donghong, Hao, Weilong, Xie, Youming
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850318/
https://ncbi.nlm.nih.gov/pubmed/26961882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.716175
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