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Rapidly Translated Polypeptides Are Preferred Substrates for Cotranslational Protein Degradation

Nascent polypeptides are degraded by the proteasome concurrently with their synthesis on the ribosome. This process, called cotranslational protein degradation (CTPD), has been observed for years, but the underlying mechanisms remain poorly understood. Equally unclear are the identities of cellular...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ha, Seung-Wook, Ju, Donghong, Hao, Weilong, Xie, Youming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850318/
https://ncbi.nlm.nih.gov/pubmed/26961882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.716175
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