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Proteasomal Degradation of Rpn4 in Saccharomyces cerevisiae Is Critical for Cell Viability Under Stressed Conditions

The proteasome homeostasis in Saccharomyces cerevisiae is regulated by a negative feedback loop in which the transcription factor Rpn4 induces the proteasome genes and is rapidly degraded by the assembled proteasome. In addition to the proteasome genes, Rpn4 regulates numerous other genes involved i...

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Detalles Bibliográficos
Main Authors: Wang, Xiaogang, Xu, Haiming, Ha, Seung-Wook, Ju, Donghong, Xie, Youming
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828715/
https://ncbi.nlm.nih.gov/pubmed/19933873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.112227
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