Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector

Heterotrimeric G proteins play an essential role in the initiation of G protein-coupled receptor (GPCR) signaling through specific interactions with a variety of cellular effectors. We have recently reported that GPCR activation promotes a direct interaction between Gαq and protein kinase C ζ (PKCζ)...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Sánchez-Fernández, Guzmán, Cabezudo, Sofía, Caballero, Álvaro, García-Hoz, Carlota, Tall, Gregory G., Klett, Javier, Michnick, Stephen W., Mayor, Federico, Ribas, Catalina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850291/
https://ncbi.nlm.nih.gov/pubmed/26887939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684308
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