Protein Kinase C (PKC)ζ-mediated Gα(q) Stimulation of ERK5 Protein Pathway in Cardiomyocytes and Cardiac Fibroblasts

Gq-coupled G protein-coupled receptors (GPCRs) mediate the actions of a variety of messengers that are key regulators of cardiovascular function. Enhanced Gα(q)-mediated signaling plays an important role in cardiac hypertrophy and in the transition to heart failure. We have recently described that G...

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Main Authors: García-Hoz, Carlota, Sánchez-Fernández, Guzmán, García-Escudero, Ramón, Fernández-Velasco, María, Palacios-García, Julia, Ruiz-Meana, Marisol, Díaz-Meco, Maria Teresa, Leitges, Michael, Moscat, Jorge, García-Dorado, David, Boscá, Lisardo, Mayor, Federico, Ribas, Catalina
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293562/
https://ncbi.nlm.nih.gov/pubmed/22232556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.282210
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