Assembly of High Order Gα(q)-Effector Complexes with RGS Proteins

Transmembrane signaling through Gα(q)-coupled receptors is linked to physiological processes such as cardiovascular development and smooth muscle function. Recent crystallographic studies have shown how Gα(q) interacts with two activation-dependent targets, p63RhoGEF and G protein-coupled receptor k...

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Bibliographische Detailangaben
Hauptverfasser: Shankaranarayanan, Aruna, Thal, David M., Tesmer, Valerie M., Roman, David L., Neubig, Richard R., Kozasa, Tohru, Tesmer, John J. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Mechanisms of Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596395/
https://ncbi.nlm.nih.gov/pubmed/18936096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805860200
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