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Structural and Functional Analysis of the Regulator of G Protein Signaling 2-Gα(q) Complex
The heterotrimeric G protein Gα(q) is a key regulator of blood pressure, and excess Gα(q) signaling leads to hypertension. A specific inhibitor of Gα(q) is the GTPase activating protein (GAP) known as regulator of G protein signaling 2 (RGS2). The molecular basis for how Gα(q/11) subunits serve as s...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638996/ https://ncbi.nlm.nih.gov/pubmed/23434405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.12.016 |
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