Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)

“Regulator of G-protein signaling” (RGS) proteins facilitate the termination of G protein-coupled receptor (GPCR) signaling via their ability to increase the intrinsic GTP hydrolysis rate of Gα subunits (known as GTPase-accelerating protein or “GAP” activity). RGS2 is unique in its in vitro potency...

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Bibliografski detalji
Glavni autori: Kimple, Adam J., Soundararajan, Meera, Hutsell, Stephanie Q., Roos, Annette K., Urban, Daniel J., Setola, Vincent, Temple, Brenda R. S., Roth, Bryan L., Knapp, Stefan, Willard, Francis S., Siderovski, David P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Mechanisms of Signal Transduction
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740565/
https://ncbi.nlm.nih.gov/pubmed/19478087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.024711
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