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Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits

Regulator of G protein signaling (RGS) proteins accelerate GTP hydrolysis by Gα subunits and thus facilitate termination of signaling initiated by G protein-coupled receptors (GPCRs). RGS proteins hold great promise as disease intervention points, given their signature role as negative regulators of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Soundararajan, Meera, Willard, Francis S., Kimple, Adam J., Turnbull, Andrew P., Ball, Linda J., Schoch, Guillaume A., Gileadi, Carina, Fedorov, Oleg Y., Dowler, Elizabeth F., Higman, Victoria A., Hutsell, Stephanie Q., Sundström, Michael, Doyle, Declan A., Siderovski, David P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359823/
https://ncbi.nlm.nih.gov/pubmed/18434541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801508105
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