Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits

Regulator of G protein signaling (RGS) proteins accelerate GTP hydrolysis by Gα subunits and thus facilitate termination of signaling initiated by G protein-coupled receptors (GPCRs). RGS proteins hold great promise as disease intervention points, given their signature role as negative regulators of...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Soundararajan, Meera, Willard, Francis S., Kimple, Adam J., Turnbull, Andrew P., Ball, Linda J., Schoch, Guillaume A., Gileadi, Carina, Fedorov, Oleg Y., Dowler, Elizabeth F., Higman, Victoria A., Hutsell, Stephanie Q., Sundström, Michael, Doyle, Declan A., Siderovski, David P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359823/
https://ncbi.nlm.nih.gov/pubmed/18434541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801508105
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky