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RGS4 and GAIP are GTPase-activating proteins for G(qα) and block activation of phospholipase Cβ by γ-thio-GTP-G(qα)

RGS proteins constitute a newly appreciated and large group of negative regulators of G protein signaling. Four members of the RGS family act as GTPase-activating proteins (GAPs) with apparent specificity for members of the G(iα) subfamily of G protein subunits. We demonstrate here that two RGS prot...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hepler, John R., Berman, David M., Gilman, Alfred G., Kozasa, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19528/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012799/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.428
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