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RGS4 and GAIP are GTPase-activating proteins for G(qα) and block activation of phospholipase Cβ by γ-thio-GTP-G(qα)

RGS proteins constitute a newly appreciated and large group of negative regulators of G protein signaling. Four members of the RGS family act as GTPase-activating proteins (GAPs) with apparent specificity for members of the G(iα) subfamily of G protein subunits. We demonstrate here that two RGS prot...

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Detalhes bibliográficos
Main Authors: Hepler, John R., Berman, David M., Gilman, Alfred G., Kozasa, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19528/
https://ncbi.nlm.nih.gov/pubmed/9012799
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