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Attenuation of G(i)- and G(q)-mediated signaling by expression of RGS4 or GAIP in mammalian cells

Protein regulators of G protein signaling (RGS proteins) were discovered as negative regulators of heterotrimeric G protein-mediated signal transduction in yeast and worms. Experiments with purified recombinant proteins in vitro have established that RGS proteins accelerate the GTPase activity of ce...

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Detalles Bibliográficos
Main Authors: Huang, Chunfa, Hepler, John R., Gilman, Alfred G., Mumby, Susanne M.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC21019/
https://ncbi.nlm.nih.gov/pubmed/9177187
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