Attenuation of G(i)- and G(q)-mediated signaling by expression of RGS4 or GAIP in mammalian cells

Protein regulators of G protein signaling (RGS proteins) were discovered as negative regulators of heterotrimeric G protein-mediated signal transduction in yeast and worms. Experiments with purified recombinant proteins in vitro have established that RGS proteins accelerate the GTPase activity of ce...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Huang, Chunfa, Hepler, John R., Gilman, Alfred G., Mumby, Susanne M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9177187/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.12.6159
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