ERK5 Activation by Gq-Coupled Muscarinic Receptors Is Independent of Receptor Internalization and β-Arrestin Recruitment

G-protein-coupled receptors (GPCRs) are known to activate both G protein- and β-arrestin-dependent signalling cascades. The initiation of mitogen-activated protein kinase (MAPK) pathways is a key downstream event in the control of cellular functions including proliferation, differentiation, migratio...

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Detalhes bibliográficos
Main Authors: Sánchez-Fernández, Guzmán, Cabezudo, Sofía, García-Hoz, Carlota, Tobin, Andrew B., Mayor Jr, Federico, Ribas, Catalina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866124/
https://ncbi.nlm.nih.gov/pubmed/24358341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084174
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