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Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum (ER) in Response to ER Stress and B Cell Stimulation
Torsin ATPases are the only representatives of the AAA+ ATPase family that reside in the lumen of the endoplasmic reticulum (ER) and nuclear envelope. Two of these, TorsinA and TorsinB, are anchored to the ER membrane by virtue of an N-terminal hydrophobic domain. Here we demonstrate that the imposi...
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Publicado en: | J Biol Chem |
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Autores principales: | , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850287/ https://ncbi.nlm.nih.gov/pubmed/26953341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709337 |
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