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Arresting a Torsin ATPase Reshapes the Endoplasmic Reticulum
Torsins are membrane-tethered AAA+ ATPases residing in the nuclear envelope (NE) and endoplasmic reticulum (ER). Here, we show that the induction of a conditional, dominant-negative TorsinB variant provokes a profound reorganization of the endomembrane system into foci containing double membrane str...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879577/ https://ncbi.nlm.nih.gov/pubmed/24275647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515791 |
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