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Arresting a Torsin ATPase Reshapes the Endoplasmic Reticulum

Torsins are membrane-tethered AAA+ ATPases residing in the nuclear envelope (NE) and endoplasmic reticulum (ER). Here, we show that the induction of a conditional, dominant-negative TorsinB variant provokes a profound reorganization of the endomembrane system into foci containing double membrane str...

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Autori principali: Rose, April E., Zhao, Chenguang, Turner, Elizabeth M., Steyer, Anna M., Schlieker, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879577/
https://ncbi.nlm.nih.gov/pubmed/24275647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515791
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