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Regulation of Torsin ATPases by LAP1 and LULL1

TorsinA is a membrane-associated AAA+ (ATPases associated with a variety of cellular activities) ATPase implicated in primary dystonia, an autosomal-dominant movement disorder. We reconstituted TorsinA and its cofactors in vitro and show that TorsinA does not display ATPase activity in isolation; AT...

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Chenguang, Brown, Rebecca S. H., Chase, Anna R., Eisele, Markus R., Schlieker, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637692/
https://ncbi.nlm.nih.gov/pubmed/23569223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300676110
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