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Dynamic functional assembly of the Torsin AAA+ ATPase and its modulation by LAP1
TorsinA is an essential AAA+ ATPase requiring LAP1 or LULL1 as cofactors. The dynamics of the Torsin/cofactor system remain poorly understood, with previous models invoking Torsin/cofactor assemblies with fixed stoichiometries. Here we demonstrate that TorsinA assembles into homotypic oligomers in t...
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| Veröffentlicht in: | Mol Biol Cell |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638581/ https://ncbi.nlm.nih.gov/pubmed/28814508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-05-0281 |
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