Dynamic functional assembly of the Torsin AAA+ ATPase and its modulation by LAP1

TorsinA is an essential AAA+ ATPase requiring LAP1 or LULL1 as cofactors. The dynamics of the Torsin/cofactor system remain poorly understood, with previous models invoking Torsin/cofactor assemblies with fixed stoichiometries. Here we demonstrate that TorsinA assembles into homotypic oligomers in t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Biol Cell
Prif Awduron: Chase, Anna R., Laudermilch, Ethan, Wang, Jimin, Shigematsu, Hideki, Yokoyama, Takeshi, Schlieker, Christian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2017
Pynciau:
Brief Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638581/
https://ncbi.nlm.nih.gov/pubmed/28814508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-05-0281
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