Access of torsinA to the inner nuclear membrane is activity dependent and regulated in the endoplasmic reticulum

TorsinA (also known as torsin-1A) is a membrane-embedded AAA+ ATPase that has an important role in the nuclear envelope lumen. However, most torsinA is localized in the peripheral endoplasmic reticulum (ER) lumen where it has a slow mobility that is incompatible with free equilibration between ER su...

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Udgivet i:J Cell Sci
Main Authors: Goodchild, Rose E., Buchwalter, Abigail L., Naismith, Teresa V., Holbrook, Kristen, Billion, Karolien, Dauer, William T., Liang, Chun-Chi, Dear, Mary Lynn, Hanson, Phyllis I.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540951/
https://ncbi.nlm.nih.gov/pubmed/26092934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.167452
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