Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum (ER) in Response to ER Stress and B Cell Stimulation

Torsin ATPases are the only representatives of the AAA+ ATPase family that reside in the lumen of the endoplasmic reticulum (ER) and nuclear envelope. Two of these, TorsinA and TorsinB, are anchored to the ER membrane by virtue of an N-terminal hydrophobic domain. Here we demonstrate that the imposi...

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Foilsithe in:J Biol Chem
Main Authors: Zhao, Chenguang, Brown, Rebecca S. H., Tang, Chih-Hang Anthony, Hu, Chih-Chi Andrew, Schlieker, Christian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2016
Ábhair:
Membrane Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850287/
https://ncbi.nlm.nih.gov/pubmed/26953341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709337
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