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A critical examination of the “bad luck” explanation of cancer risk
Tomasetti and Vogelstein (1) argue that lifetime cancer risk for particular tissues is mostly determined by the total number of stem cell (SC) divisions within the tissue, whereby most cancers arise due to “bad luck” – mutations occurring during DNA replication. We argue that the poorly substantiate...
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| Publicat a: | Cancer Prev Res (Phila) |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849411/ https://ncbi.nlm.nih.gov/pubmed/26122457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-15-0229 |
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