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Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations
Our understanding of cancer has greatly advanced since Nordling [Nordling CO (1953) Br J Cancer 7(1):68–72] and Armitage and Doll [Armitage P, Doll R (1954) Br J Cancer 8(1):1–12] put forth the multistage model of carcinogenesis. However, a number of observations remain poorly understood from the st...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517250/ https://ncbi.nlm.nih.gov/pubmed/26195756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501713112 |
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