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The evolution of lifespan and age-dependent cancer risk

The Armitage-Doll multi-stage model of carcinogenesis tremendously refocused cancer science by postulating that carcinogenesis is driven by a sequence of genetic changes in cells. Age-dependent cancer incidence thus has been explained in terms of the time necessary for oncogenic mutations to occur....

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Detalhes bibliográficos
Publicado no:Trends Cancer
Main Authors: Rozhok, Andrii I., DeGregori, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400291/
https://ncbi.nlm.nih.gov/pubmed/28439564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.09.004
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