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Studying the regulation of endosomal cAMP production in GPCR signaling

We describe methods based on live cell fluorescent microscopy and mass spectrometry to characterize the mechanism of endosomal cAMP production and its regulation using the parathyroid hormone (PTH) type 1 receptor as a prime example. These methods permit to measure rapid changes of cAMP levels in re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Methods Cell Biol
Egile Nagusiak: Gidon, Alexandre, Feinstein, Timothy N., Xiao, Kunhong, Vilardaga, Jean-Pierre
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848751/
https://ncbi.nlm.nih.gov/pubmed/26928541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mcb.2015.10.007
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