Ex vivo expansion of circulating CD34(+) cells enhances the regenerative effect on rat liver cirrhosis

Ex vivo expansion of autologous cells is indispensable for cell transplantation therapy of patients with liver cirrhosis. The aim of this study was to investigate the efficacy of human ex vivo-expanded CD34(+) cells for treatment of cirrhotic rat liver. Recipient rats were intraperitoneally injected...

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Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Nakamura, Toru, Koga, Hironori, Iwamoto, Hideki, Tsutsumi, Victor, Imamura, Yasuko, Naitou, Masako, Masuda, Atsutaka, Ikezono, Yu, Abe, Mitsuhiko, Wada, Fumitaka, Sakaue, Takahiko, Ueno, Takato, Ii, Masaaki, Alev, Cantas, Kawamoto, Atsuhiko, Asahara, Takayuki, Torimura, Takuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847556/
https://ncbi.nlm.nih.gov/pubmed/27162932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.25
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