Antiangiogenic and Antitumor Activities of Aflibercept, a Soluble VEGF Receptor-1 and -2, in a Mouse Model of Hepatocellular Carcinoma

BACKGROUND & AIM: Aflibercept known as ziv-aflibercept in the United States is a soluble decoy receptor of both vascular endothelial growth factor (VEGF) receptor-1 and -2 known to inhibit the binding of VEGF and placental growth factor (PlGF) to VEGF receptor-1 and -2. Here, we analyzed the mec...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Torimura, Takuji, Iwamoto, Hideki, Nakamura, Toru, Abe, Mitsuhiko, Ikezono, Yu, Wada, Fumitaka, Sakaue, Takahiko, Masuda, Hiroshi, Hashimoto, Osamu, Koga, Hironori, Ueno, Takato, Yano, Hirohisa
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2016
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954942/
https://ncbi.nlm.nih.gov/pubmed/27435924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.05.001
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