STAT3 deficiency prevents hepatocarcinogenesis and promotes biliary proliferation in thioacetamide-induced liver injury

AIM: To elucidate the role of STAT3 in hepatocarcinogenesis and biliary ductular proliferation following chronic liver injury. METHODS: We investigated thioacetamide (TAA)-induced liver injury, compensatory hepatocyte proliferation, and hepatocellular carcinoma (HCC) development in hepatic STAT3-def...

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Vydáno v:World J Gastroenterol
Hlavní autoři: Abe, Mitsuhiko, Yoshida, Takafumi, Akiba, Jun, Ikezono, Yu, Wada, Fumitaka, Masuda, Atsutaka, Sakaue, Takahiko, Tanaka, Toshimitsu, Iwamoto, Hideki, Nakamura, Toru, Sata, Michio, Koga, Hironori, Yoshimura, Akihiko, Torimura, Takuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2017
Témata:
Basic Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645616/
https://ncbi.nlm.nih.gov/pubmed/29085226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i37.6833
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