STAT3 deficiency prevents hepatocarcinogenesis and promotes biliary proliferation in thioacetamide-induced liver injury

AIM: To elucidate the role of STAT3 in hepatocarcinogenesis and biliary ductular proliferation following chronic liver injury. METHODS: We investigated thioacetamide (TAA)-induced liver injury, compensatory hepatocyte proliferation, and hepatocellular carcinoma (HCC) development in hepatic STAT3-def...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:World J Gastroenterol
Main Authors: Abe, Mitsuhiko, Yoshida, Takafumi, Akiba, Jun, Ikezono, Yu, Wada, Fumitaka, Masuda, Atsutaka, Sakaue, Takahiko, Tanaka, Toshimitsu, Iwamoto, Hideki, Nakamura, Toru, Sata, Michio, Koga, Hironori, Yoshimura, Akihiko, Torimura, Takuji
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2017
Teme:
Basic Study
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645616/
https://ncbi.nlm.nih.gov/pubmed/29085226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i37.6833
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki