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The Complexity of the ERK/MAP-Kinase Pathway and the Treatment of Melanoma Skin Cancer
The central role played by the ERK/MAPK pathway downstream of RAS in human neoplasias is best exemplified in the context of melanoma skin cancer. Signaling through the MAPK pathway is crucial for the proliferation of melanocytes, the healthy pigment cells that give rise to melanoma. However, hyper-a...
Gespeichert in:
| Veröffentlicht in: | Front Cell Dev Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846800/ https://ncbi.nlm.nih.gov/pubmed/27200346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00033 |
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