Mitochondrial common deletion is elevated in blood of breast cancer patients mediated by oxidative stress

The 4,977 bp common deletion is one of the most frequently observed mitochondrial DNA (mtDNA) mutations in human tissues and has been implicated in various human cancer types. It is generally believed that continuous generation of intracellular reactive oxygen species (ROS) during oxidative phosphor...

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Pubblicato in:Mitochondrion
Autori principali: Nie, Hezhongrong, Chen, Guorong, He, Jing, Zhang, Fengjiao, Li, Ming, Wang, Qiufeng, Zhou, Huaibing, Lyu, Jianxin, Bai, Yidong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846287/
https://ncbi.nlm.nih.gov/pubmed/26678158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2015.12.001
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