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Mitochondrial DNA 4977-base pair common deletion in blood leucocytes and melanoma risk
The 4977-base pair common deletion DmtDNA4977 is the most frequently observed mitochondrial DNA mutation in human tissues. Because mitochondrial DNA mutations are mainly caused by reactive oxygen species (ROS), and given that oxidative stress plays an important role in melanoma carcinogenesis, the i...
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| Udgivet i: | Pigment Cell Melanoma Res |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520800/ https://ncbi.nlm.nih.gov/pubmed/26988264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12474 |
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