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Mitochondrial DNA 4977-base pair common deletion in blood leucocytes and melanoma risk

The 4977-base pair common deletion DmtDNA4977 is the most frequently observed mitochondrial DNA mutation in human tissues. Because mitochondrial DNA mutations are mainly caused by reactive oxygen species (ROS), and given that oxidative stress plays an important role in melanoma carcinogenesis, the i...

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Detalhes bibliográficos
Publicado no:Pigment Cell Melanoma Res
Main Authors: Shen, Jie, Wan, Jie, Huff, Chad, Fang, Shenying, Lee, Jeffrey E., Zhao, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520800/
https://ncbi.nlm.nih.gov/pubmed/26988264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12474
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