Mitochondrial Common Deletion, a Potential Biomarker for Cancer Occurrence, Is Selected against in Cancer Background: A Meta-Analysis of 38 Studies

Mitochondrial dysfunction has been long proposed to play a major role in tumorigenesis. Mitochondrial DNA (mtDNA) mutations, especially the mtDNA 4,977 bp deletion has been found in patients of various types of cancer. In order to comprehend the mtDNA 4,977 bp deletion status in various cancer types...

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Detalhes bibliográficos
Main Authors: Nie, Hezhongrong, Shu, Hongying, Vartak, Rasika, Milstein, Amanda Claire, Mo, Yalin, Hu, Xiaoqin, Fang, Hezhi, Shen, Lijun, Ding, Zhinan, Lu, Jianxin, Bai, Yidong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701633/
https://ncbi.nlm.nih.gov/pubmed/23861839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067953
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