The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer

BACKGROUND: Qualitative and quantitative changes in human mitochondrial DNA (mtDNA) have been implicated in various cancer types. A 4,977 bp deletion in the major arch of the mitochondrial genome is one of the most common mutations associated with a variety of human diseases and aging. METHODS: We c...

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Main Authors: Chen, Tao, He, Jing, Shen, Lijun, Fang, Hezhi, Nie, Hezhongrong, Jin, Tao, Wei, Xiaosong, Xin, Yijuan, Jiang, Yulin, Li, Hongzhi, Chen, Guorong, Lu, Jianxin, Bai, Yidong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025938/
https://ncbi.nlm.nih.gov/pubmed/21232124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-8
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