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Detection of mitochondrial DNA with 4977 bp deletion in leukocytes of patients with ischemic stroke

BACKGROUND: Coronary artery disease is associated with a common mitochondrial DNA alteration, a 4977 bp deletion (mtDNA(4977)). The role of mtDNA(4977) in ischemic stroke is unknown. METHODS: Real-time quantitative PCR was performed to quantify total mtDNA and mtDNA(4977) in leukocytes in 283 ischem...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Huang, Yu-hua, Chen, Chiung-Mei, Lee, Yun-Shien, Chang, Kuo-Hsuan, Chen, Huei-Wen, Chen, Yi-Chun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825052/
https://ncbi.nlm.nih.gov/pubmed/29474453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193175
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